Contrast enhanced MRI technology finds leakages in blood brain barrier

Q.  Researchers have used a contrast enhanced MRI technique to find leagues in the BBB. What does BBB stand for in the context of Alzheimer’s?
- Published on 01 Jun 16

a. Blood Brain Barrier
b. Brain Blood Barrier
c. Blood Brain Barricade
d. Brain Blood Barricade

ANSWER: Blood Brain Barrier
 
Researchers using a contrast-enhanced MRI technique have found that leakages in the blood-brain barrier (BBB) may lead to early onset of Alzheimer's disease (AD).
  • The BBB - a collection of cells and subcellular structures that separates the circulating blood from the brain - is essential to keep brain tissue in healthy condition.
  • It regulates the delivery of important nutrients and blocks neurotoxins, while removing surplus substances from the brain.
  • The results suggest that increased BBB permeability may represent a key mechanism in the early stages of the Alzheimer's disease, the researchers said.
  • Further, the more impairment in BBB lead to greater decline in cognitive performance in patients.

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