Scientists grow living bone in lab to repair large defects
Q. Scientists have grown a living _____ in the lab for repairing large defects in head and face- Published on 20 Jun 16a. Bone
b. Frontal Lobe
c. Cartilage
d. Brain
ANSWER: Bone
In the first, scientists have grown a living bone in the lab to repair large defects in the head and face of patients, taking a move forward in enhancing treatments for persons with craniofacial defects.
- New technique developed by Columbia University researchers uses autologous stem cells derived from a little sample of the recipient’s fat and replicates the anatomical structure of the bone
- Researchers also include scientists from Louisiana State University and Tulane University in the US fabricated scaffold and bioreactor chamber based on jaw defects to yield perfect anatomical fit
- Scaffold built enabled bone formation without the use of growth factors and also provided mechanical function which has a unique application for clinicians.
- The recipients own stem cells can be isolated from the small fat aspirate and form the bone within a scaffold made from bone matrix in a custom designed perfused bioreactor
- The outcome was that the lab grown bone when implanted was replaced by a new bone formed by the body
- This result was not seen with the implantation of the scaffold alone without cells.
- Researchers now include a cartilage layer in the bio-engineered living bone tissue to study bone regeneration in complex defects of the head and face.
