Fast acting Rabishield drug developed by Pune’s SII in collaboration with University of Massachusetts medical school

Q.  Pune based Serum Institute of India has collaborated with which US university’s medical school for developing the first fast acting anti rabies drug of the world and what is it called?
- Published on 25 Feb 16

a. Duke University, RMAb
b. University of Massachusetts, Rabieshield
c. University of Massachusetts, RMAb
d. Both b and c
e. None of the above

ANSWER: Both b and c
 
The first fast acting anti rabies drug of the world which deactivates the deadly virus and provides protection in the case of severe dog bites, has been developed by Pune’s Serum Institute of India and US based Mass Biologics of the University of Massachusetts Medical School. Drug us called RMAb or rabies human monoclonal antibody or Rabishield. It precludes chances of transmitting blood none infections there in rabies immunoglobulin, a current treatment option for severe dog bites. Drug has been manufactured through the use of recombinant DNA technology and is 25% cheaper than existing rabies immunoglobulins which means it will meet needs of developed countries. In India around 20,000 deaths are caused by rabies each year. WHO estimates that 55,000 deaths are caused by rabies in Africa and Asia each year. The new drug is suitable for severe dog bite cases because it is an human IgG1 monoclonal antibody that specifically binds to a conformational epitope of G glycoprotein of rabies virus and instantly deactivates it.

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