Human protein NLRX1 weakens immune response to HIV

Q.  Recently a protein has been discovered that weakens immune response to HIV. The protein is?
- Published on 03 May 16

a. MCR-1
b. MCR2H
c. NLRX1
d. NLRX3

ANSWER: NLRX1
 
  • Deficiencies in NLRX1 - an intracellular protein - reduce HIV replication, suggesting that the development of small molecules to modulate the innate immune response may inhibit viral transmission and promote immunity to infection.
  • This research expands understanding of the role of host proteins in viral replication and the innate immune response to HIV infection, and can be extended to DNA viruses such as HSV and vaccinia.

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