Researchers identify new innate immune pathway offering protection from cancer

Q.  What is autophagy?
- Published on 14 Mar 16

a. Cellular housekeeping process
b. Process where body’s cell destroy damaged proteins and organelles
c. Both of the above
d. None of the above

ANSWER: Both of the above
 
Researchers have identified a new innate immune technology pathway protecting mammals from viral oncogenesis through a process by which viruses cause normal cells to become cancerous. This discovery could open new frontiers for cancer treatment. Autphagy related protein beclin 2 discovered by researchers can damage key oncogenic viral protein associated with Kapok’s sarcoma, a certain kind of cancer. Autophagy is a cellular housekeeping process where the cells of the body destroy damaged proteins and organelles. In addition to mediating autophagy, beclin 2 is also part of an immune pathway that promoted degradation of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor (GPCR), and thereby suppress its cancer-causing signalling," said Dong.

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