Scientists identify cGAS enzyme as major cause of autoimmune diseases

Q.  Scientists have located which enzyme as the major culprit of autoimmune diseases on 2nd November 2015?
- Published on 03 Nov 15

a. cDAS
b. cGAS
c. cJAS
d. None of the above

ANSWER: cGAS
 
Inhibition of enzyme cGAS will be effective therapy for autoimmune diseases such as SLE and AGS linked to the same inflammatory pathway. The immune system turns against the body rather than protecting it in these diseases. Scientists have said that cGAS enzyme’s activation plays a key role in these diseases. Researchers also found legal autoimmunity as a result of inability to degrade lysosomal DNA through lack of DNA digesting enzyme referred to as DNase-II.

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